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NEJM paper published - trial guidelines

13 February 2020   (0 Comments)
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The New England Journal of Medicine has published an article from researchers from the Nuffield Department of Population Health (University of Oxford) focused on the need for randomised controlled trials as well as the need for appropriate trial guidelines. 

Access the article here: https://www.nejm.org/doi/full/10.1056/NEJMsb1901642

"Non-randomized observational analyses have been promoted as alternatives to randomized clinical trials. However, randomization ensures balance between groups, whereas non-randomized studies are often biased by between-group differences. Efforts to reduce the cost and complexity of clinical trials are preferable to relying on observational studies."