Schwartz and Lellouch were the first to use the word “pragmatic” in relation to clinical trials in 1967. They defined a pragmatic trial as a trial designed to help chose between care options, as opposed to an explanatory trial which is used to test causal research hypotheses, for example about biological processes. Thirty years later Roland and Torgerson made the distinction between these two approaches in a different way, explaining that explanatory trials evaluate efficacy, the effect of treatment in ideal conditions and pragmatic trials evaluate effectiveness, the effect of treatment in routine clinical practice. It is now recognised that there is, in fact, a spectrum of trials with very explanatory trials at one end and very pragmatic trials at the other end.
Who this course is for
Anyone involved or with an interest in the design, conduct, analysis or reporting of a pragmatic trials in the academic or NHS sector. The course will be of interest to all investigators, researchers, statisticians, trial managers, research nurses and PhD students.
Location: PCTU, Yvonne Carter Building, 58 Turner Street, E1 2AB
Availability: Limited places
Cost: £200 external, £150 for QMUL staff
Registration is now open:
For further information and to register your interest please visit https://www.qmul.ac.uk/pctu/courses-and-events/introduction-to-pragmatic-trials/#d.en.763156 or contact firstname.lastname@example.org